Sample Evidence Map
Query: endometrial organoid implantation. Public metadata only. Manual verification is required before citation or manuscript use.
| Evidence | Year | Paper | Rationale | Support sentence |
|---|---|---|---|---|
| model system evidence | 2017 | Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium. | Foundational paper; high citation count; public PMCID available. | Despite the importance of the endometrium as the site of implantation and nutritional support for the conceptus, there are no long-term culture systems that recapitulate endometrial function in vitro. |
| model system evidence | 2021 | Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids. | Query term overlap; endometrial assembloid implantation model. | Our findings suggest that decidual senescence controls endometrial fate decisions at implantation. |
| model system evidence | 2026 | Mechanistic Insights Into Recurrent Implantation Failure via Endometrial Organoid and Blastoid-Endometrial Cell Implantation Models. | Recent-mode top result; direct organoid and implantation model match. | Leveraging multiple organoid systems, including endometrial organoids and blastoid-endometrial cell implantation models. |